RE57091_IFU_en_Rubella IgM ELISA_VN2011_08_sym3
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Optimal Timing of Specimen Collection after Rash Onset for Diagnosis of Measles IgM Antibody
Antibody detection is the most versatile and commonly used method for measles diagnosis. Detection of specific IgM antibodies in a single serum specimen collected within the appropriate time after rash onset can provide a good presumptive diagnosis of current or recent measles infection and is the test of choice for rapid diagnosis of measles cases. So, optimal timing for collection of a sing...
متن کاملDetection of Toxoplasma Parasitemia by PCR: Does it Correlate with IgG and IgM Antibody Titers?
Background: Toxoplasmosis is a zoonotic disease with high seroprevalence worldwide. Several immunological methods have been described for diagnosis of toxoplasmosis. Objective: To determine the parasitemia period in patients infected with toxoplasma using PCR and comparing serological data with molecular results. Methods: 154 serum samples from patients with toxoplasmosis were examined. Presenc...
متن کاملنقش IgM و IgG ضد توکسوپلاسما در سقط جنین
57 women affected by abortion or threatened abortion were investigated in view of antitoxoplasmosis antibodies by immunofluorscence. 11 women who have aborted for the first time have positive titer of polyvalent antibodies more than 1/400. 77.3% of these women have IgM titer greater than 1/20. The highest percentage of abortion was in the third month of pregnancy and this is probabley related t...
متن کاملCharacterization of a large fragment produced by proteolysis of human immunoglobulin M with papain.
The controlled digestion of human immunoglobulin M (IgM) (Patient Dau.) with papain in the presence of 0.002 M mercaptoethylamine resulted in the release of a basic subunit-like fragment which we designated IgM,. It resembled the subunit (IgM,) produced by mild reduction of IgM in the following ways. The molecular weight (186,000) and sedimentation coefficient (6.2 to 6.5 S) of IgM, were simila...
متن کاملLow molecular weight IgM in primary biliary cirrhosis.
Low molecular weight IgM is the monomeric subunit of pentameric IgM and is not generally found in the blood of healthy individuals. Using a sensitive immunoblotting technique, low molecular weight IgM was detected in all 17 patients with primary biliary cirrhosis and constituted up to 5% of the total circulating IgM. This low molecular weight IgM moiety correlated significantly with total IgM (...
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